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Astellas Pharma Research Associate II, In Vivo in Seattle, Washington

Universal Cells is focused on the development and commercialization of stem cell and regenerative medicine therapies. We conduct clinical-grade gene editing of stem cells and have a major effort in R&D. We design and produce stem cells that avoid rejection, and we engineer cells with improved therapeutic properties, all through our world-class gene editing platform.

Our goal is to provide cells for regenerative medicine applications that can treat all patients. Through internal R&D and our corporate partnerships, we are pursuing a diverse range of disease indications, including blindness, cancer, vascular insufficiency, and autoimmune diseases.

Universal Cells (UCI) is announcing a Research Associate II, In Vivo opportunity at their facility in Seattle, WA.

Purpose:

The primary purpose of the Research Associate II is to perform in vivo studies supporting the development of novel stem cell derived cellular therapies. This position will work primarily in a laboratory setting with Scientist and R&D teams.

Universal Cells is a wholly-owned subsidiary of Astellas Pharma. Astellas is an R&D-driven global pharmaceutical company whose philosophy is to contribute to the improvement of people's health around the world through the provision of innovative and reliable pharmaceutical products.

Essential Job Responsibilities:

  • Participates in developing, optimizing and troubleshooting in vivo models of oncology and autoimmunity in rodents
  • Performs and interprets preclinical efficacy studies, including dosing, measurements, and post-procedural monitoring
  • Collaborates with supervisory personnel to design, schedule, and execute in vivo experiments
  • Performs experiments with a careful attention to detail
  • Accurately records procedures, data, and results
  • Interprets data, draws conclusions from experimental work, and presents in team meetings
  • Collaborates across teams within R&D, and other teams within Universal Cells
  • Performs other duties as assigned or special projects as needed

Qualifications:

Required

  • BS degree with 3+ years or MS with 0-2 years of laboratory experience
  • Hands-on experience with in vivo models of oncology, immunology and autoimmunity, including proficiency in multiple routes of administration (IM, ID, SC, IV, etc.), organ and tissue harvesting, and blood collection techniques
  • Ability to review, comprehend, and comply with all standard operation procedures (SOPs) and quality assurance standards pertaining to laboratory animals
  • Diligence, and meticulous attention to detail in experimentation and record keeping
  • Willingness to learn and enthusiasm to be part of the development of a cutting-edge therapy platform
  • Ability to analyze and interpret data
  • Strong organizational, time management, problem solving skills and the ability to work on several projects simultaneously
  • Ability to work independently with supervision and ability to effectively collaborate across teams
  • Excellent communication and interpersonal skills and genuine care for animals
  • AALAS certification a plus

Preferred

  • Strong scientific training and laboratory skills in stem cell biology, immunology, immuno-oncology, and oncology
  • Hands-on experience with ex vivo tissue processing, including immune cell isolation and characterization by flow cytometry, multiplex immunohistochemistry, and other ex vivo assays
  • Experience with in vivo imaging techniques
  • Experience in cell culture and cell line maintenance

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Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled

Category Research and Development

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